翻訳と辞書 Words near each other ・ Serule ・ Serum ・ Serum (blood) ・ Serum albumin ・ Serum amyloid A ・ Serum amyloid A1 ・ Serum amyloid P component ・ Serum chloride ・ Serum free light-chain measurement ・ Serum Institute of India ・ Serum iron ・ Serum Metabolome Database ・ Serum protein electrophoresis ・ Serum response factor ・ Serum sickness ・ Serum sickness-like reaction ・ Serum total protein ・ Serum-ascites albumin gradient ・ Serum-derived bovine immunoglobulin/protein isolate ・ Serum-separating tube ・ Serumakkanallur ・ Serumavilangai ・ Serundeng ・ Serupane ・ Serupepeli Naqase ・ Serutan ・ Seruthunai Nayanar ・ Seruvakula ・ Seruvalsar and Manimahesh Lake ・ Seruvila Divisional Secretariat Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Serum sickness-like reaction ： ウィキペディア英語版 Serum sickness-like reaction Serum sickness-like reactions refer to adverse reactions that have similar symptoms to serum sickness, but in which immune complexes are not found.〔James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.〕 == Pathogenesis == Serum sickness-like reaction is named for its clinical similarity to serum sickness, in which immune complexes are deposited in the skin, joints, and other organs. True serum sickness, a type III hypersensitivity reaction, results in fever, lymphadenopathy, arthralgias,cutaneous eruptions, gastrointestinal disturbances, proteinuria,and significant decreases in serum complement levels; it was originally described after patients were infused with equine immunoglobulins. In contrast, serum sickness-like reactions are specific drug reactions that are not associated with circulating immune complexes. Although the exact pathogenesis is poorly understood, serum sickness-like reactions are thought to originate from an abnormal inflammatory reaction that occurs in response to defective metabolism of drug byproducts generated during pharmacologic therapy; the metabolic flaw could be a maternally-inherited trait. In vivo hepatic drug biotransformation studies have shown greater lymphocyte killing in subjects with a known history of serum sickness-like reactions than in control subjects. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Serum sickness-like reaction」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.